Astragalin attenuates caerulein-induced acute pancreatitis by targeting the NLRP3 signaling pathway and gut microbiota

Abstract Background Acute pancreatitis (AP) has caused great concern worldwide due to its serious threat to human health. Astragalin is a bioactive natural flavonoid compound with several pharmacological activities, but it remains unclear about its effect on AP. The objective of this experiment was...

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Autors principals:	Yan Jia, Yuxin Shi, Jie Wang, Honghui Liu, Hanyue Wang, Yilin Huang, Ya Liu, Peiyan Chen, Jie Peng
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2025-12-01
Col·lecció:	Bioresources and Bioprocessing
Matèries:	Astragalin Acute pancreatitis Gut microbiota Network pharmacology NLRP3 signaling pathway
Accés en línia:	https://doi.org/10.1186/s40643-025-00977-3
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