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POGZ suppresses 2C transcriptional program and retrotransposable elements

Summary: The POGZ gene has been found frequently mutated in neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and intellectual disability (ID). We have recently shown that POGZ maintains mouse embryonic stem cells (ESCs). However, the exact mechanisms remain unclear. Here, w...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xiaoyun Sun, Tianzhe Zhang, Bei Tong, Linxi Cheng, Wei Jiang, Yuhua Sun
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2023-08-01
Rangatū:Cell Reports
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124723008781
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