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Smarcb1 Loss Results in a Deregulation of esBAF Binding and Impacts the Expression of Neurodevelopmental Genes

The murine esBAF complex plays a major role in the regulation of gene expression during stem cell development and differentiation. As one of its core subunits, Smarcb1 is indispensable for its function and its loss is connected to neurodevelopmental disorders and participates in the carcinogenesis o...

Celý popis

Uloženo v:
Hlavní autoři: Amelie Alfert, Carolin Walter, Natalia Moreno, Viktoria Melcher, Monika Graf, Marc Hotfilder, Martin Dugas, Thomas Albert, Kornelius Kerl
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-04-01
Edice:Cells
Témata:
Smarcb1
BAF complex
embryonic stem cells
chromatin remodelling
ChIP-seq
On-line přístup:https://www.mdpi.com/2073-4409/11/8/1354
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