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8OHdG as a marker for Huntington disease progression

Leukocyte 8-hydroxydeoxyguanosine (8OHdG) is an indicator of oxidative stress, impaired metabolism, and mitochondrial dysfunction, features that have been implicated in Huntington disease (HD). Increased levels of 8OHdG have been reported in the caudate, parietal cortex, and peripherally in the seru...

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Bibliografische Detailangaben
Hauptverfasser: Jeffrey D. Long, Wayne R. Matson, Andrew R. Juhl, Blair R. Leavitt, Jane S. Paulsen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2012-06-01
Schriftenreihe:Neurobiology of Disease
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0969996112000678
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