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Automated determination of 8-OHdG in cells and tissue via immunofluorescence using a specially created antibody

Despite powerful DNA repair systems, oxidative damage/modification to DNA is an inevitable side effect of metabolism, ionizing radiation, lifestyle habits, inflammatory pathologies such as type-2 diabetes or metabolic syndrome, cancer and natural aging.One of the most common oxidative DNA modificati...

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Main Authors: Tobias Jung, Nicole Findik, Bianca Hartmann, Katja Hanack, Kai Grossmann, Dirk Roggenbuck, Marc Wegmann, René Mantke, Markus Deckert, Tilman Grune
Format: Artigo
Language:Inglês
Published: Elsevier 2024-06-01
Series:Biotechnology Reports
Subjects:
8-OHdG
DNA-damage
Immunostaining
Histology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X24000067
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