The toxin–antitoxin complex Fic‐1–AntF functions as a deAMPylase that regulates the activity of DNA gyrase

Abstract Toxin–antitoxin (TA) systems found in diverse bacteria play important roles in their adaptation to changing environments. The toxin of the Fic‐1–AntF TA pair from Pseudomonas bijieensis strain 2P24 inhibits bacterial DNA replication by attacking the subunit B of DNA gyrase (GyrB) via AMPyla...

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Auteurs principaux:	Furong Chen, Liwei Guo, Canhua Lu, Wenjun Jiang, Zhao‐Qing Luo, Junfeng Liu, Li‐Qun Zhang
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2026-06-01
Collection:	mLife
Sujets:	AMPylation deAMPylation Fic protein post‐translational modification toxin–antitoxin
Accès en ligne:	https://doi.org/10.1002/mlf2.70085
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