Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on glutathione synthetase

Radix Bupleuri (RB) is commonly used to treat depression, but it can also lead to hepatotoxicity after long-term use. In many anti-depression prescriptions, RB is often used in combination with Radix Paeoniae Alba (RPA) as an herb pair. However, whether RPA can alleviate RB-induced hepatotoxicity re...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Congcong Chen, Wenxia Gong, Junshen Tian, Xiaoxia Gao, Xuemei Qin, Guanhua Du, Yuzhi Zhou
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2023-06-01
Serija:	Journal of Pharmaceutical Analysis
Teme:	Radix Bupleuri Radix Paeoniae Alba Hepatotoxicity Gut microbiota Saikosaponins Combination mechanisms
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2095177923000837
Oznake:	Označite Brez oznak, prvi označite!