Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis

Abstract Background Upregulation of an RNA-binding protein HuR has been implicated in glomerular diseases. Herein, we evaluated whether it is involved in renal tubular fibrosis. Methods HuR was firstly examined in human kidney biopsy tissue with tubular disease. Second, its expression and the effect...

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Hlavní autoři:	Zhimin Huang, Simeng Liu, Anna Tang, Xiaoqing Wu, Jeffrey Aube, Liang Xu, Yufeng Huang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-06-01
Edice:	Journal of Translational Medicine
Témata:	RNA-binding protein HuR inhibitor Ischemia–reperfusion Renal fibrosis Chronic kidney disease
On-line přístup:	https://doi.org/10.1186/s12967-023-04298-x
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