Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous seizure

Abstract Epileptogenesis is the process by which a normal brain becomes hyperexcitable and capable of generating spontaneous recurrent seizures. The extensive dysregulation of gene expression associated with epileptogenesis is shaped, in part, by microRNAs (miRNAs) – short, non-coding RNAs that nega...

Повний опис

Бібліографічні деталі

Автори:	Niraj Khemka, Gareth Morris, Laleh Kazemzadeh, Lara S. Costard, Valentin Neubert, Sebastian Bauer, Felix Rosenow, Morten T. Venø, Jørgen Kjems, David C. Henshall, Jochen H. M. Prehn, Niamh M. C. Connolly
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Nature Portfolio 2024-07-01
Серія:	Scientific Reports
Предмети:	Epilepsy Epileptogensis microRNA miRNA-mRNA interactions Bayesian modelling Temporal expression profiling
Онлайн доступ:	https://doi.org/10.1038/s41598-024-66117-7
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!