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E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy

Ubiquitination is a dynamic post-translational modification that regulates the fate of proteins and therefore modulates a myriad of cellular functions. At the last step of this sophisticated enzymatic cascade, E3 ubiquitin ligases selectively direct ubiquitin attachment to specific substrates. Altog...

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書目詳細資料
Principais autores: Léa Lescouzères, Pascale Bomont
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020-10-01
叢編:Frontiers in Physiology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fphys.2020.01022/full
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