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Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity

The segregation of the readily releasable pool of synaptic vesicles (RRP) in sub-pools that are differentially poised for exocytosis shapes short-term plasticity. However, the frequency-dependent mobilization of these sub-pools is poorly understood. Using slice recordings and modeling of synaptic ac...

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Principais autores: Frédéric Doussau, Hartmut Schmidt, Kevin Dorgans, Antoine M Valera, Bernard Poulain, Philippe Isope
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2017-10-01
coleção:eLife
Assuntos:
cerebellum
short-term plasticity
Purkinje cell
parallel fibers
neurotransmitter release
synaptic vesicles
Acesso em linha:https://elifesciences.org/articles/28935
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