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Effect of astaxanthin in type-2 diabetes -induced APPxhQC transgenic and NTG mice

Objectives: Aggregation and misfolding of amyloid beta (Aβ) and tau proteins, suggested to arise from post-translational modification processes, are thought to be the main cause of Alzheimer's disease (AD). Additionally, a plethora of evidence exists that links metabolic dysfunctions such as obesity...

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Asıl Yazarlar: Joshua Adekunle Babalola, Anika Stracke, Tina Loeffler, Irene Schilcher, Spyridon Sideromenos, Stefanie Flunkert, Joerg Neddens, Ake Lignell, Manuela Prokesch, Ute Pazenboeck, Herbert Strobl, Jelena Tadic, Gerd Leitinger, Achim Lass, Birgit Hutter-Paier, Gerald Hoefler
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2024-07-01
Seri Bilgileri:Molecular Metabolism
Konular:
Alzheimer's disease
Type 2 diabetes
Pyroglutamylation
Metabolic perturbation
Astaxanthin
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2212877824000905
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