Effect of astaxanthin in type-2 diabetes -induced APPxhQC transgenic and NTG mice

Objectives: Aggregation and misfolding of amyloid beta (Aβ) and tau proteins, suggested to arise from post-translational modification processes, are thought to be the main cause of Alzheimer's disease (AD). Additionally, a plethora of evidence exists that links metabolic dysfunctions such as obesity...

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Principais autores:	Joshua Adekunle Babalola, Anika Stracke, Tina Loeffler, Irene Schilcher, Spyridon Sideromenos, Stefanie Flunkert, Joerg Neddens, Ake Lignell, Manuela Prokesch, Ute Pazenboeck, Herbert Strobl, Jelena Tadic, Gerd Leitinger, Achim Lass, Birgit Hutter-Paier, Gerald Hoefler
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-07-01
Serija:	Molecular Metabolism
Teme:	Alzheimer's disease Type 2 diabetes Pyroglutamylation Metabolic perturbation Astaxanthin
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2212877824000905
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