Impaired airway epithelial miR-155/BACH1/NRF2 axis and hypoxia gene expression during RSV infection in children with down syndrome

BackgroundChildren with Down Syndrome (DS) are at high risk for severe respiratory syncytial virus (RSV) infections. DS is associated with impaired cellular responses to oxidative stress and hypoxia; however, these abnormalities have not been explored in trisomy 21 (TS21) airway epithelial cells (AE...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Allison Welham, Elizabeth Chorvinsky, Surajit Bhattacharya, Kyle Salka, Betelehem Solomon Bera, Woudasie Admasu, Maria C. Straker, Maria J. Gutierrez, Jyoti K. Jaiswal, Gustavo Nino
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2025-05-01
Цуврал:	Frontiers in Pediatrics
Нөхцлүүд:	trisomy 21 (Down syndrome) RSV (respiratory syncytial virus) airway epithelia miR-155 hypoxia
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fped.2025.1553571/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!