Trehalose Phosphate Synthase Complex-Mediated Regulation of Trehalose 6-Phosphate Homeostasis Is Critical for Development and Pathogenesis in Magnaporthe oryzae

ABSTRACT Trehalose biosynthesis pathway is a potential target for antifungal drug development, and trehalose 6-phosphate (T6P) accumulation is widely known to have toxic effects on cells. However, how organisms maintain a safe T6P level and cope with its cytotoxicity effects when accumulated have no...

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Những tác giả chính:	Xin Chen, Yakubu Saddeeq Abubakar, Chengdong Yang, Xiaxia Wang, Pengfei Miao, Mei Lin, Yuetong Wen, Qiuqiu Wu, Haoming Zhong, Yuping Fan, Meiru Zhang, Zonghua Wang, Jie Zhou, Wenhui Zheng
Định dạng:	Artigo
Ngôn ngữ:	Inglês
Được phát hành:	American Society for Microbiology 2021-10-01
Loạt:	mSystems
Những chủ đề:	cell wall integrity fungal development Magnaporthe oryzae trehalose 6-phosphate homeostasis spontaneous mutation TPS complex
Truy cập trực tuyến:	https://journals.asm.org/doi/10.1128/msystems.00462-21
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