Trehalose Phosphate Synthase Complex-Mediated Regulation of Trehalose 6-Phosphate Homeostasis Is Critical for Development and Pathogenesis in Magnaporthe oryzae

ABSTRACT Trehalose biosynthesis pathway is a potential target for antifungal drug development, and trehalose 6-phosphate (T6P) accumulation is widely known to have toxic effects on cells. However, how organisms maintain a safe T6P level and cope with its cytotoxicity effects when accumulated have no...

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Hlavní autoři:	Xin Chen, Yakubu Saddeeq Abubakar, Chengdong Yang, Xiaxia Wang, Pengfei Miao, Mei Lin, Yuetong Wen, Qiuqiu Wu, Haoming Zhong, Yuping Fan, Meiru Zhang, Zonghua Wang, Jie Zhou, Wenhui Zheng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2021-10-01
Edice:	mSystems
Témata:	cell wall integrity fungal development Magnaporthe oryzae trehalose 6-phosphate homeostasis spontaneous mutation TPS complex
On-line přístup:	https://journals.asm.org/doi/10.1128/msystems.00462-21
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