Trehalose Phosphate Synthase Complex-Mediated Regulation of Trehalose 6-Phosphate Homeostasis Is Critical for Development and Pathogenesis in Magnaporthe oryzae

ABSTRACT Trehalose biosynthesis pathway is a potential target for antifungal drug development, and trehalose 6-phosphate (T6P) accumulation is widely known to have toxic effects on cells. However, how organisms maintain a safe T6P level and cope with its cytotoxicity effects when accumulated have no...

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Bibliografiske detaljer

Principais autores:	Xin Chen, Yakubu Saddeeq Abubakar, Chengdong Yang, Xiaxia Wang, Pengfei Miao, Mei Lin, Yuetong Wen, Qiuqiu Wu, Haoming Zhong, Yuping Fan, Meiru Zhang, Zonghua Wang, Jie Zhou, Wenhui Zheng
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology 2021-10-01
Serier:	mSystems
Fag:	cell wall integrity fungal development Magnaporthe oryzae trehalose 6-phosphate homeostasis spontaneous mutation TPS complex
Online adgang:	https://journals.asm.org/doi/10.1128/msystems.00462-21
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