QR-Code

Intracellular Delivery of Short Interfering RNA in Rat Organ of Corti Using a Cell-penetrating Peptide PepFect6

RNA interference (RNAi) using short interfering RNA (siRNA) is an attractive therapeutic approach for treatment of dominant-negative mutations. Some rare missense dominant-negative mutations lead to congenital-hearing impairments. A variety of viral vectors have been tested with variable efficacy fo...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Suvarna Dash-Wagh, Stefan Jacob, Staffan Lindberg, Anders Fridberger, Ülo Langel, Mats Ulfendahl
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2012-01-01
Schriftenreihe:Molecular Therapy: Nucleic Acids
Schlagworte:
cell-penetrating peptide (CPP)
cochlea
connexin
FRAP
gap junctions
gene therapy
inner ear
nanoparticles
siRNA
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2162253116301160
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge