PepFect14 mediates the delivery of mRNA into human primary keratinocytes and in vivo

mRNA-based vaccines and candidate therapeutics have great potential in various medical fields. For the delivery of mRNA into target cells and tissues, lipid formulations are often employed. However, this approach could cause the activation of immune responses, making it unsuitable for the treatment...

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Autors principals:	Kapilraj Periyasamy, Maria Maloverjan, Abhijit Biswas, Anu Remm, Martin Pook, Ana Rebane, Margus Pooga
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-07-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	cell-penetrating peptides mRNA delivery transfection nanoparticles skin inflammatory diseases endocytosis inhibitors
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1219761/full
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