Introduction of plasmid encoding for rare tRNAs reduces amplification bias in phage display biopanning

Amplification bias is a major hurdle in phage display protocols because it imparts additional, unintended selection pressure beyond binding to the desired target. One potential source of amplification bias is the inherent lack of codon optimization that occurs within phage display libraries. Here we...

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Detaylı Bibliyografya
Asıl Yazarlar:	Benjamin J. Umlauf, Michael J. McGuire, Kathlynn C. Brown
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis Group 2015-02-01
Seri Bilgileri:	BioTechniques
Konular:	phage display amplification bias codon bias peptide combinatorial peptide libraries biopanning
Online Erişim:	https://www.future-science.com/doi/10.2144/000114256
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Introduction of plasmid encoding for rare tRNAs reduces amplification bias in phage display biopanning

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