Neoglycoconjugate of Tetrasaccharide Representing One Repeating Unit of the Streptococcus pneumoniae Type 14 Capsular Polysaccharide Induces the Production of Opsonizing IgG1 Antibodies and Possesses the Highest Protective Activity As Compared to Hexa- and Octasaccharide Conjugates

Identifying protective synthetic oligosaccharide (OS) epitopes of Streptococcus pneumoniae capsular polysaccharides (CPs) is an indispensable step in the development of third-generation carbohydrate pneumococcal vaccines. Synthetic tetra-, hexa-, and octasaccharide structurally related to CP of S. p...

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Detaylı Bibliyografya

Asıl Yazarlar:	Ekaterina A. Kurbatova, Nelli K. Akhmatova, Elina A. Akhmatova, Nadezhda B. Egorova, Natalya E. Yastrebova, Elena V. Sukhova, Dmitriy V. Yashunsky, Yury E. Tsvetkov, Marina L. Gening, Nikolay E. Nifantiev
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2017-06-01
Seri Bilgileri:	Frontiers in Immunology
Konular:	Streptococcus pneumoniae type 14 synthetic oligosaccharide glycoconjugate vaccine protective activity antibody specificity opsonophagocytosis biotinylated oligosaccharide
Online Erişim:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00659/full
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