S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (<it>P. anubis</it>)
<p>Abstract</p> <p>Background</p> <p>S110 is a novel dinucleoside analog that could have advantages over existing DNA methyltransferase (DNMT) inhibitors such as decitabine. A potential therapeutic role for S110 is to increase fetal hemoglobin (HbF) levels to treat β-hemoglobinopathies. In these exp...
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| Principais autores: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2010-10-01
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| Serier: | Journal of Translational Medicine |
| Online adgang: | http://www.translational-medicine.com/content/8/1/92 |
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