Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer’s disease pathology

Abstract Patients with Alzheimer’s disease (AD) exhibit non-rapid eye movement (NREM) sleep disturbances in addition to memory deficits. Disruption of NREM slow waves occurs early in the disease progression and is recapitulated in transgenic mouse models of beta-amyloidosis. However, the mechanisms...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yee Fun Lee, Alyssa N. Russ, Qiuchen Zhao, Stephen J. Perle, Megi Maci, Morgan R. Miller, Steven S. Hou, Moustafa Algamal, Zhuoyang Zhao, Hanyan Li, Noah Gelwan, Zhe Liu, Stephen N. Gomperts, Alfonso Araque, Elena Galea, Brian J. Bacskai, Ksenia V. Kastanenka
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2023-08-01
Цуврал:	Scientific Reports
Онлайн хандалт:	https://doi.org/10.1038/s41598-023-40402-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!