Synthesis of Substituted 1,4-Benzodiazepines by Palladium-Catalyzed Cyclization of <i>N</i>-Tosyl-Disubstituted 2-Aminobenzylamines with Propargylic Carbonates

A synthesis of substituted 1,4-benzodiazepines has been developed via palladium-catalyzed cyclization of <i>N</i>-tosyl-disubstituted 2-aminobenzylamines with propargylic carbonates. The reaction proceeds through the formation of π-allylpalladium intermediates, which undergo intramolecular nucleophi...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Masahiro Yoshida, Saya Okubo, Akira Kurosaka, Shunya Mori, Touya Kariya, Kenji Matsumoto
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-07-01
Edice:	Molecules
Témata:	1,4-benzodiazepine cascade reaction cyclization palladium catalyst propargylic carbonate
On-line přístup:	https://www.mdpi.com/1420-3049/30/14/3004
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!