Engineering Single-Chain Antibody Fragment (scFv) Variants Targeting A Disintegrin and Metalloproteinase-17 (ADAM-17)

Metalloproteinases (MPs) are zinc-dependent endopeptidases, including matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinases (ADAMs), implicated in various diseases such as cancer, neurodegenerative disorders, and cardiovascular conditions. Among MPs, ADAM-17, also known as tumor...

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Bibliografische Detailangaben

Hauptverfasser:	Masoud Kalantar, Elham Khorasani Buxton, Korey M. Reid, Donald Bleyl, David M. Leitner, Maryam Raeeszadeh-Sarmazdeh
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-12-01
Schriftenreihe:	Biomolecules
Schlagworte:	metalloproteinase antibody engineering ADAM-17 directed evolution single-chain variable fragment (scFv) yeast surface display
Online-Zugang:	https://www.mdpi.com/2218-273X/16/1/31
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