SWATH-MS insights on sodium butyrate effect on mAbs production and redox homeostasis in CHO cells

Abstract Sodium butyrate (NaBu), well-known as a histone deacetylase inhibitor and for its capacity to impede cell growth, can enhance the production of a specific protein, such as an antibody, in recombinant Chinese hamster ovary (CHO) cell cultures. In this study, two CHO cell lines, namely K1 and...

Description complète

Détails bibliographiques

Auteurs principaux:	Mauro Galli, Lillian Chia-Yi Liu, Kae Hwan Sim, Yee Jiun Kok, Katherine Wongtrakul-Kish, Terry Nguyen-Khuong, Stephen Tate, Xuezhi Bi
Format:	Artigo
Langue:	Inglês
Publié:	SpringerOpen 2024-12-01
Collection:	AMB Express
Sujets:	Butyric acid CHO cells SWATH-MS Redox mAbs
Accès en ligne:	https://doi.org/10.1186/s13568-024-01807-z
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!