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Stress‐induced increase of monoclonal antibody production in CHO cells

Abstract Monoclonal antibodies (mAbs) are of great interest to the biopharmaceutical industry due to their widely used application as human therapeutic and diagnostic agents. As such, mAb require to exhibit human‐like glycolization patterns. Therefore, recombinant Chinese hamster ovary (CHO) cells a...

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Principais autores: Jana Schellenberg, Tamanna Nagraik, Ole Jacob Wohlenberg, Sebastian Ruhl, Janina Bahnemann, Thomas Scheper, Dörte Solle
Format: Artigo
Sprog:Inglês
Udgivet: Maximum Academic Press 2022-05-01
Serier:Engineering in Life Sciences
Fag:
cell size
cell‐specific productivity
CHO
mAb
stress
Online adgang:https://doi.org/10.1002/elsc.202100062
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