Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein

<p>Abstract</p> <p>Background</p> <p>Retroviruses HTLV-1 and HTLV-2 have homologous genomic structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell Leukemia (ATL), whereas infection by HTLV-2 has no association with neoplasia. Transformation of T lymphocytes by H...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Turci Marco, Lodewick Julie, Di Gennaro Gianfranco, Rinaldi Anne, Marin Oriano, Diani Erica, Sampaio Carla, Bex Françoise, Bertazzoni Umberto, Romanelli Maria
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2012-12-01
سلاسل:	Retrovirology
الموضوعات:	HTLV-1 HTLV-2 Retrovirus Tax Oncoprotein Leukemia Post-translational modification Ubiquitination Sumoylation NF-κB pathway
الوصول للمادة أونلاين:	http://www.retrovirology.com/content/9/1/102
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!