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Move or Die: the Fate of the Tax Oncoprotein of HTLV-1

The HTLV-1 Tax protein both activates viral replication and is involved in HTLV-1-mediated transformation of T lymphocytes. The transforming properties of Tax include altering the expression of select cellular genes via activation of cellular pathways and perturbation of both cell cycle control mech...

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Principais autores: Françoise Bex, Isabelle Lamsoul, Julie Lodewick
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2011-06-01
Serier:Viruses
Fag:
HTLV-1
Tax
retrovirus
signal transduction
NF-kB
nuclear bodies
intracellular trafficking
posttranslational modifications
leukemia
Online adgang:http://www.mdpi.com/1999-4915/3/6/829/
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