Targeting NEDD8-activating enzyme for cancer therapy: developments, clinical trials, challenges and future research directions
Abstract NEDDylation, a post-translational modification through three-step enzymatic cascades, plays crucial roles in the regulation of diverse biological processes. NEDD8-activating enzyme (NAE) as the only activation enzyme in the NEDDylation modification has become an attractive target to develop...
Kaydedildi:
| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2023-07-01
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| Seri Bilgileri: | Journal of Hematology & Oncology |
| Konular: | |
| Online Erişim: | https://doi.org/10.1186/s13045-023-01485-7 |
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