Evaluation of galantamine and deconstructed analogs as α7 nAChR and AChE ligands
Galantamine (1), one of only five agents currently approved for the treatment of Alzheimer’s disease, is thought to act primarily as an inhibitor of acetylcholinesterase (AChE) and possibly as a positive allosteric modulator (PAM) of neuronal α7 nicotinic acetylcholine (nACh) receptors. Here, the st...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2022-01-01
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| Series: | Results in Chemistry |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2211715622000054 |
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