Inhibiting CXCR6 promotes senescence of activated hepatic stellate cells with limited proinflammatory SASP to attenuate hepatic fibrosis

This study investigates the previously unexplored role of CXC chemokine receptor 6 (CXCR6) in hepatic fibrosis, where excessive extracellular matrix deposition by activated hepatic stellate cells (aHSCs) drives disease progression. Through analysis of gene expression omnibus datasets and human fibro...

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Xehetasun bibliografikoak

Egile Nagusiak:	Sheng Liqin, Wu Yiming, Shen Fei, Xu Chenzhou
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	De Gruyter 2025-08-01
Saila:	Open Life Sciences
Gaiak:	hepatic stellate cells senescence sasp cxcr6 hepatic fibrosis
Sarrera elektronikoa:	https://doi.org/10.1515/biol-2025-1151
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