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In Vitro Lipid Overload Affects Cellular Proliferation, Apoptosis, and Senescence in a Time-Dependent Manner in HepG2 Hepatocytes and LX-2 Hepatic Stellate Cells

Different cellular mechanisms influence steatotic liver disease (SLD) progression. The influence of different levels of steatogenic inputs has not been studied in hepatocytes and hepatic stellate cells (HSCs). Methods: HepG2 hepatocytes and LX-2 HSCs were cultured in mild (MS) and severe (SS) steato...

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Autori principali: Adriana Campos-Espinosa, Carolina Guzmán, Karla Zaira Medina-Ávila, Gabriela Gutierrez-Reyes
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-02-01
Serie:Cells
Soggetti:
steatosis
hepatocytes
hepatic stellate cells
apoptosis
proliferation
senescence
Accesso online:https://www.mdpi.com/2073-4409/13/3/282
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