A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory

We present a multi-scale model of the within-phagocyte, within-host and population-level infection dynamics of Francisella tularensis, which extends the mechanistic one proposed by Wood et al. (2014). Our multi-scale model incorporates key aspects of the interaction between host phagocytes and extra...

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Autores principales:	Jonathan Carruthers, Martín López-García, Joseph J. Gillard, Thomas R. Laws, Grant Lythe, Carmen Molina-París
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2018-07-01
Colección:	Frontiers in Microbiology
Materias:	Francisella tularensis Markov process multi-scale model dose response probability mean response time zonal ventilation model
Acceso en línea:	https://www.frontiersin.org/article/10.3389/fmicb.2018.01165/full
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