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Modelling early events in Francisella tularensis pathogenesis

Computational models can provide valuable insights into the mechanisms of infection and be used as investigative tools to support development of medical treatments. We develop a stochastic, within-host, computational model of the infection process in the BALB/c mouse, following inhalational exposure...

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Hlavní autoři: Grant eLythe, Joseph eGillard, Thomas eLaws, Carmen eMolina-Paris
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014-12-01
Edice:Frontiers in Cellular and Infection Microbiology
Témata:
Francisella tularensis
Lung Diseases
Macrophages
Pathogenesis
Stochastic Modeling
compartmental models
On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00169/full
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