Broad-spectrum ubiquitin-specific protease inhibition as a mechanism for the cytotoxicity of YM155 in cancers

Abstract Protein ubiquitination is a dynamic and reversible process involved in gene transcription, protein metabolism, and cellular apoptosis. Ubiquitin specific proteases (USPs), as the largest family of deubiquitinating enzymes, are able to remove the ubiquitin from target proteins, rescuing them...

全面介绍

书目详细资料

Principais autores:	Xiang Li, Na He, Yan Lv, Haiyue Wang, Ming Zhang, Heiyan Zhai, Zhen Yang, Yi Yang, Dagang Guo, Zhixiang Cao, Yiyou Chen
格式:	Artigo
语言:	Inglês
出版:	Nature Portfolio 2025-04-01
丛编:	Scientific Reports
主题:	YM155 A broad-spectrum USP inhibitor c-Myc Notch1 Ubiquitin-proteasome pathway
在线阅读:	https://doi.org/10.1038/s41598-025-88761-3
标签:	添加标签 没有标签, 成为第一个标记此记录!