Lactadherin mediates sickle cell adhesion to vascular endothelial cells in flowing blood

Increased exposure of sickle red blood cells to phosphatidylserine promotes its adhesion to the endothelium. A monoclonal antibody to lactadherin, a phosphatidylserine binding protein, inhibits sickle cell adhesion to histamine-stimulated endothelial cells in flowing blood. Added lactadherin enhance...

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Autors principals:	Prasenjit Guchhait, Swapan K Dasgupta, Anhquyen Le, Sarvari Yellapragada, José A. López, Perumal Thiagarajan
Format:	Artigo
Idioma:	Inglês
Publicat:	Ferrata Storti Foundation 2007-09-01
Col·lecció:	Haematologica
Accés en línia:	https://haematologica.org/article/view/4573
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