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Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

The TTT complex is composed of the three essential proteins Tel2, Tti1, and Tti2. The complex is required to maintain steady state levels of phosphatidylinositol 3-kinase-related kinase (PIKK) proteins, including mTOR, ATM/Tel1, ATR/Mec1, and TRRAP/Tra1, all of which serve as regulators of critical...

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Principais autores: Kyle S. Hoffman, Martin L. Duennwald, Jim Karagiannis, Julie Genereaux, Alexander S. McCarton, Christopher J. Brandl
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016-06-01
Serier:G3: Genes, Genomes, Genetics
Fag:
TTT complex
PIKK proteins
heat shock response
chaperone
protein expression
Online adgang:http://g3journal.org/lookup/doi/10.1534/g3.116.029520
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