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Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution

Coactivator complexes SAGA and NuA4 stimulate transcription by post-translationally modifying chromatin. Both complexes contain the Tra1 subunit, a highly conserved 3744-residue protein from the Phosphoinositide 3-Kinase-related kinase (PIKK) family and a direct target for multiple sequence-specific...

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書誌詳細
主要な著者: Luis Miguel Díaz-Santín, Natasha Lukoyanova, Emir Aciyan, Alan CM Cheung
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications Ltd 2017-08-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/28384
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