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Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells

Objectives: While glucagon-like peptide-1 (GLP-1) production has been previously documented in human alpha cells, the steps regulating its production and secretion are poorly characterized. We investigated the enzymes implicated in proglucagon processing, characterizing their expression and localiza...

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Bibliografische gegevens
Hoofdauteurs: Janyne Koepke, Wentong Long, Amy Barr, Peter E. Light
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2025-12-01
Reeks:Molecular Metabolism
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Online toegang:http://www.sciencedirect.com/science/article/pii/S2212877825001668
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