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Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells

Objectives: While glucagon-like peptide-1 (GLP-1) production has been previously documented in human alpha cells, the steps regulating its production and secretion are poorly characterized. We investigated the enzymes implicated in proglucagon processing, characterizing their expression and localiza...

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Autors principals: Janyne Koepke, Wentong Long, Amy Barr, Peter E. Light
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2025-12-01
Col·lecció:Molecular Metabolism
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2212877825001668
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