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Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells

Objectives: While glucagon-like peptide-1 (GLP-1) production has been previously documented in human alpha cells, the steps regulating its production and secretion are poorly characterized. We investigated the enzymes implicated in proglucagon processing, characterizing their expression and localiza...

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Principais autores: Janyne Koepke, Wentong Long, Amy Barr, Peter E. Light
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-12-01
coleção:Molecular Metabolism
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2212877825001668
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