The RP11-417E7.1/THBS2 signaling pathway promotes colorectal cancer metastasis by activating the Wnt/β-catenin pathway and facilitating exosome-mediated M2 macrophage polarization

Abstract Background Metastasis is the major cause of colorectal cancer (CRC) mortality. Emerging evidence suggests that long noncoding RNAs (lncRNAs) drive cancer metastasis and that their regulatory pathways could be targeted for preventing metastasis. However, the underlying mechanisms of lncRNAs...

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Autori principali:	Yunze Liu, Heng Lv, Xin Liu, Lei Xu, Tiankang Li, Hui Zhou, Hongmei Zhu, Chuanchuan Hao, Changwei Lin, Yi Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-07-01
Serie:	Journal of Experimental & Clinical Cancer Research
Soggetti:	RP11-417E7.1 Colorectal cancer Metastasis Macrophage polarization Wnt/β-catenin Netropsin
Accesso online:	https://doi.org/10.1186/s13046-024-03107-7
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