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NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway

Abstract Objectives The NEK2 (never in mitosis gene A-related kinase 2), a serine/threonine kinase involved in chromosome instability and tumorigenesis. Hence, this study aimed to explore the molecular function of NEK2 in esophageal squamous cell carcinoma (ESCC). Methods By available transcriptome...

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Principais autores: Dong Guo, Weinan Yao, Xingyu Du, Jing Dong, Xueyuan Zhang, Wenbin Shen, Shuchai Zhu
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2023-05-01
Serier:Discover Oncology
Fag:
NEK2
Invasion
Wnt/β-catenin
Esophageal squamous cell carcinoma
Proliferation
Online adgang:https://doi.org/10.1007/s12672-023-00692-5
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