Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.
Heart failure is associated with impairment in nitric oxide (NO) mediated vasodilatation, which has been demonstrated to result from a reduction in the relative expression of the leucine zipper positive (LZ+) isoform of the myosin targeting subunit (MYPT1) of myosin light chain phosphatase. Further,...
Bewaard in:
| Hoofdauteurs: | , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2009-01-01
|
| Reeks: | PLoS ONE |
| Online toegang: | http://europepmc.org/articles/PMC2663051?pdf=render |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|