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Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.

Heart failure is associated with impairment in nitric oxide (NO) mediated vasodilatation, which has been demonstrated to result from a reduction in the relative expression of the leucine zipper positive (LZ+) isoform of the myosin targeting subunit (MYPT1) of myosin light chain phosphatase. Further,...

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Bibliográfalaš dieđut
Váldodahkkit: Erhan Ararat, Frank V Brozovich
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2009-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC2663051?pdf=render
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