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Thrombin enhances NGF-mediated neurite extension via increased and sustained activation of p44/42 MAPK and p38 MAPK.

Rapid neurite remodeling is fundamental to nervous system development and plasticity. It involves neurite extension that is regulated by NGF through PI3K/AKT, p44/42 MAPK and p38 MAPK. It also involves neurite retraction that is regulated by the serine protease, thrombin. However, the intracellular...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Rania E Mufti, Krishna Sarker, Yan Jin, Songbin Fu, Jesusa L Rosales, Ki-Young Lee
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2014-01-01
Цуврал:PLoS ONE
Онлайн хандалт:http://europepmc.org/articles/PMC4111596?pdf=render
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