Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase

Abstract Vitamin K-dependent (VKD) carboxylation, mediated by γ-glutamyl carboxylase (GGCX), is essential for the maturation of VKD proteins involved in critical physiological processes such as blood clotting, vascular calcification and bone metabolism. Here, we present cryo-electron microscopic str...

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Xehetasun bibliografikoak

Egile Nagusiak:	Ke Wu, Zheng Wang, Deqiang Yao, Shaobai Li, Xiaozhu Wang, Yuanyuan Zhang, Mi Cao, Yafeng Shen, Shunpeng Xing, Jian Wu, Ming Lei, Pengfei Lan
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2025-11-01
Saila:	Nature Communications
Sarrera elektronikoa:	https://doi.org/10.1038/s41467-025-65488-3
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