Capillary Zone Electrophoresis with Light-Emitting Diode-Induced Fluorescence Detection for the Analysis of Monoclonal Antibodies: Detector Optimization through Design of Experiments and Comparison to UV Detection

Capillary zone electrophoresis (CZE) is an important technique for the analysis of monoclonal antibodies (mAbs). A recently released light-emitting diode (LED)-induced fluorescence (LEDIF) detector equipped with a 275 nm LED for the detection of proteins through their native fluorescence was used in...

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Asıl Yazarlar:	Holger Zagst, Sophie Hartung, Dina-Mareike Menges, Antonia Wittmann, Hermann Wätzig
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	MDPI AG 2023-05-01
Seri Bilgileri:	Separations
Konular:	capillary zone electrophoresis monoclonal antibody LED-induced fluorescence design of experiments charge heterogeneity
Online Erişim:	https://www.mdpi.com/2297-8739/10/5/320
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