Age-related STING suppression in macrophages contributes to increased viral load during influenza a virus infection

Abstract Ageing is a major risk factor that contributes to increased mortality and morbidity rates during influenza A virus (IAV) infections. Macrophages are crucial players in the defense against viral infections and display impaired function during ageing. However, the impact of ageing on macropha...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Thurid Lauf, Antje Häder, Franziska Hornung, Yasmina Reisser, Sandor Nietzsche, Fabian Schanz, Verena Trümper, Aldona Jeznach, Sascha Brunke, Torsten Doenst, Tomasz Skirecki, Bettina Löffler, Stefanie Deinhardt-Emmer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-11-01
Serie:	Immunity & Ageing
Soggetti:	Influenza A virus Mitochondria cGAS-STING pathway Ageing Macrophages
Accesso online:	https://doi.org/10.1186/s12979-024-00482-9
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!